ELISA Substrates and Reagents
Neogen Diagnostics Custom TMB Substrate, 200 ML, HRP, Microwell, Colorimetric
Custom TMB Substrate is a one bottle stabilized chromogenic substrate for use with horseradish peroxidase (HRP) immunoassays. It contains both 3,3,5,5 tetramethylbenzidine (TMB) and hydrogen peroxide (H2O2). Custom TMB Substrate develops a deep blue color in the presence of peroxidase labelled conjugate. This substrate has been optimized for use with microwell assays, especially ELISA. Custom TMB is not for use with assays requiring a precipitating substrate. Stable for a minimum of 36-months when stored at 2-8C.
Sigma Aldrich Fine Chemicals Biosciences Interferon-gamma human hIf
IfN-I3 is produced by T-lymphocytes stimulated by antigen or by T-cell mitogens. Under nondenaturating conditions its molecular weight values range from 32 000 to 73 000 indicating that recombinant human IfN-I3 exists as a dimer or higher oligomers.
BIORBYT LLC Phospho-Tauthr217RabbitPolyclo
CategoryAntibodies.ClonalityPolyclonal.Clone---.HostRabbit
Cayman Chemical ChemerIn-9humnacetate 500ug
A peptide agonist of CMKLR1 and CMKLR2; binds to CMKLR1 and CMKLR2 (IC50s = 1.9 and 2.3 nM, respectively); induces calcium mobilization in HEK293T cells expressing either CMKLR1 or CMKLR2 and the G protein Gα15 at 1 µM
ABclonal Technology Phospho-CDK1-Y15 Rabbit pAb
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
ABclonal Technology Phospho-ACC1-S79 Rabbit pAb
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5 sequence and encoding distinct isoforms have been found for this gene.
ABclonal Technology Phospho-MAPKAPK-2/MK2-T334 Rabbit pAb
This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.
ABclonal Technology Phospho-NDRG1-T346 Rabbit pAb
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
ABclonal Technology Phospho-TP73-Y99 Rabbit pAb
This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined.
ATCC FL74-UCD-1 (CRL-8012) Feline Lymphoblastoid Cell Line, Suspension Culture
FL74-UCD-1 is a feline lymphoblastoid cancer cell line established from a cat with lymphoma. The line grows in suspension, exhibits lymphoblast morphology, and is persistently infected with a feline leukemia virus strain that produces high viral titers with attenuated virulence. It is used in virology, vaccine development, and immunology research.
- Organism: Felis catus (cat).
- Cell type: Lymphoblastoid cancer cell line.
- Morphology: Lymphoblast; suspension culture.
- Disease origin: Feline lymphoma.
- Viral status: Persistently infected with feline leukemia virus; produces high viral titers with attenuated virulence.
- Typical applications: Virology, vaccine production, immunology.
- Accession/RRID: CVCL_6391.
ABclonal Technology Phospho-ErbB4/HER4-Y1284 Rabbit pAb
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.
ABclonal Technology Phospho-MEK1-S298 Rabbit pAb
The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
Abcam 650 nm Stop Solution for TMB Substrate, 1000ML
Abcam's 650 nm Stop Solution for TMB Substrate is a ready-to-use solution for colorimetric HRP-based ELISA detection.
The product is subject to the following: Abcam Restricted Use Statement